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Codeine is an opiate used to treat pain, coughing, and diarrhea. it is typically used to treat mild to moderate degrees of pain. greater benefits may occur when combined with paracetamol (acetaminophen) or a nonsteroidal anti-inflammatory drug (nsaid) such as aspirin or ibuprofen.

Arsphenamine was first synthesized in 1907 in paul ehrlich's lab by alfred bertheim. the antisyphilitic activity of this compound was discovered by sahachiro hata in 1909, during a survey of hundreds of newly synthesized organic arsenical compounds. ehrlich had theorized that by screening many compounds, a drug could be discovered that would have anti-microbial activity …

Patients receiving the fixed combination of glyburide and metformin had greater reductions in hba 1c and fasting plasma glucose concentrations than those receiving glyburide, metformin, or placebo; at the end of the study, strict glycemic control (e.g., hba 1c values less than 7%) was achieved in 59.9, 50.4, 66.4, or 71.7% of patients receiving ...

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